There are two different versions of the remote. One has Bluetooth, the other one doesn’t. The one that doesn’t, comes with a remote USB plugin, which will allow you to connect to the box if the box has a USB port. She can “wake it up”, if it’s in sleep mode. If she turns it “off” though, probably not. I always let my boxes go to sleep, or manually put them in sleep mode. That way I can use the remote to wake the box up.
I have 4 of those remotes, and love 'em. I purchased the ones with Bluetooth and backlight features. The volume control works on my nVidia Shields, but won’t control the volume when I’m watching my FireTV, so you’ll just have to connect it to your box, and see which controls work and which ones don’t. What’s really sweet, is being able to use the keyboard to enter searches or other things you can type. You can navigate really well, with these remotes, also! They’re rechargable, so you don’t have to worry about batteries, also!